Poort, H. et al. (2016) Palliative Medicine. 30(9) pp. 897-898
Background: Fatigue is a prevalent and burdensome symptom for patients with advanced cancer. The long-term use of pharmacological interventions for fatigue is not supported by evidence, although non pharmacological and behavioral interventions are promising approaches to reducing fatigue based on their effectiveness in early-stage cancer patients. Behavioral factors, like sleeping problems and being less physically active, can also contribute to fatigue in advanced cancer patients. Interventional studies for the management of fatigue in advanced cancer patients are needed.
However, it is a notorious challenge to identify patients for interventional studies aimed at fatigue or symptom control while patients are undergoing cancer treatment with palliative intent. One of the barriers to successful identification of these patients is professional gatekeeping, due to the care professionals’ perception that study participation might be too burdensome for the patient. Although gatekeeping is done in order to prevent additional burden for patients who are seriously ill, it also limits access for patients to potentially effective interventions for fatigue and makes it difficult to develop evidence-based interventions for fatigue in advanced cancer patients.
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